Leucocyte migration test and hypersensitivity to glafenin.
PMID 30331 · Allergy · 1978 · DOI 10.1111/j.1398-9995.1978.tb01521.x
Authors: J H Saurat; L Galloppin; C Ponvert; J Paupe
Abstract
The leucocyte migration test (LMT) was performed on 20 patients with an intolerance to glafenin--a non-narcotic analgesic drug. LMT was found to be positive in 50% of the subjects with intolerance, a highly significant percentage as compared with the control groups. HSA-glafenin was found to be the most appropriate method for presenting the antigen, but glafenin and its hydroxylated metabolites were only found to induce a migration inhibition in the subjects intolerant to glafenin.
Adult; Aged; Cell Migration Inhibition; Cell Movement; Drug Hypersensitivity; Female; Glafenine; Humans; Leukocytes; Male; Middle Aged; Serum Albumin; ortho-Aminobenzoates
Cite
J H Saurat; L Galloppin; C Ponvert; J Paupe. Leucocyte migration test and hypersensitivity to glafenin. Allergy (1978). PMID 30331. DOI 10.1111/j.1398-9995.1978.tb01521.x.