Influence of pH and temperature on behaviour of surfactant from human neonatal lungs.
PMID 26432 · Biology of the neonate · 1978 · DOI 10.1159/000241058
Authors: C Meban
Abstract
The surface pressures of human surfactant films were measured under static conditions and under dynamic (expansion-compression) conditions. The results from both methods showed that the maximum surface pressures generated by surfactant films in vitro were strongly dependent on temperature throughout the range 29-41 degrees C, higher pressures being achieved at the lower temperatures. In contrast, increasing the pH of the subphase stepwise over the range 7.1-7.7 produced a modest fall in the maximum pressures exerted by the films. The possibility that surfactant films may behave in a similar manner in vivo is discussed.
Humans; Hydrogen-Ion Concentration; Infant, Newborn; Pressure; Pulmonary Surfactants; Temperature
Cite
C Meban. Influence of pH and temperature on behaviour of surfactant from human neonatal lungs. Biology of the neonate (1978). PMID 26432. DOI 10.1159/000241058.