Cardiac and bronchial beta-adrenoceptor antagonistic potencies of atenolol, metoprolol, acebutolol, practolol, propranolol and pindolol in the anaesthetized dog.
PMID 25152 · Clinical and experimental pharmacology & physiology · 1978 · DOI 10.1111/j.1440-1681.1978.tb00651.x
Authors: H H Harms; A J Spoelstra
Abstract
1. The beta-adrenoceptor antagonists atenolol, metoprolol, acebutolol, practolol, propranolol and pindolol have been tested for their ability to reduce isoprenaline-induced bronchodilation and tachycardia in the anaesthetized dog. 2. Atenolol, metoprolol, acebutolol and practolol all possessed a similar degree of cardioselectivity in this animal model.
Acebutolol; Adrenergic beta-Antagonists; Animals; Atenolol; Bronchi; Dogs; Heart; Isoproterenol; Male; Metoprolol; Pindolol; Practolol; Propranolol
Cite
H H Harms; A J Spoelstra. Cardiac and bronchial beta-adrenoceptor antagonistic potencies of atenolol, metoprolol, acebutolol, practolol, propranolol and pindolol in the anaesthetized dog. Clinical and experimental pharmacology & physiology (1978). PMID 25152. DOI 10.1111/j.1440-1681.1978.tb00651.x.