Endogenous allergen upregulation: transgenic vs. traditionally bred crops.
PMID 21784119 · Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association · 2011 · DOI 10.1016/j.fct.2011.07.018
Authors: Rod A Herman; Gregory S Ladics
Abstract
The safety assessment for transgenic food crops currently includes an evaluation of the endogenous allergy potential (via serum IgE screening) when the non-transgenic counterpart is a commonly allergenic food. The value of this analysis in the safety assessment of transgenic crops, especially with reference to recent requests to quantify individual allergen concentrations in raw commodities, is examined. We conclude that the likelihood of upregulating an endogenous allergen due to transgenesis is no greater than from traditional breeding which has a history of safety and is largely unregulated. The potential consequences of upregulating an endogenous allergen are also unclear.
Allergens; Food Hypersensitivity; Humans; Plants, Genetically Modified; Up-Regulation
Cite
Rod A Herman; Gregory S Ladics. Endogenous allergen upregulation: transgenic vs. traditionally bred crops. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association (2011). PMID 21784119. DOI 10.1016/j.fct.2011.07.018.