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[Antigenic rearrangement in the liver of mice and rats as a result of simultaneous effect of the carcinogens].

PMID 201056 · Tsitologiia · 1977

Authors: V A Ivanov; S A Avertsev; V Ia Fel'; Iu M Olenov

Abstract

The antigenic structure of the livers of mice and rats after a single hepatocarcinogenic treatment was investigated using the immunodiffuse and immunofluorescent methods. The next day after carcinogen application changes characteristic of hepatocellular tumors were observed: decrease in the synthesis of organospecific antigens and intensification of the synthesis of heteroorganic antigens.

Animals; Antigens, Neoplasm; Azo Compounds; Carcinoma, Hepatocellular; Dimethylnitrosamine; Liver; Liver Neoplasms; Male; Mice; Neoplasms, Experimental; Nitrosamines; Organ Specificity; Rats; o-Aminoazotoluene; p-Dimethylaminoazobenzene

PubMed record

Cite

V A Ivanov; S A Avertsev; V Ia Fel'; Iu M Olenov. [Antigenic rearrangement in the liver of mice and rats as a result of simultaneous effect of the carcinogens]. Tsitologiia (1977). PMID 201056.