[Relation between Beta-2-glycoprotein I and hepatitis B virus surface antigen].
PMID 11856498 · Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2002
Authors: Pujun Gao; Yanjun Guo; Like Qu; Tong Shi; Hongyan Zhang; Chun'e Dong; Hanyi Yang
Abstract
To clarify the binding character between Beta-2-glycoprotein I (Beta-2-GPI) and HBsAg. Beta-2-GPI was purified from human plasma and labelled with biotin. Solid phase enzyme linked absorbance assay was used to investigate its binding with HBsAg. Biotinylated Beta-2-GPI was found to bind HBsAg and the reaction could be inhibited by excess unlabelled Beta-2-GPI. Beta-2-GPI may play a role in hepatitis B virus infection.
Binding Sites; Biotinylation; Enzyme-Linked Immunosorbent Assay; Glycoproteins; Hepatitis B Surface Antigens; Hepatitis B virus; Humans; beta 2-Glycoprotein I
Cite
Pujun Gao; Yanjun Guo; Like Qu; Tong Shi; Hongyan Zhang; Chun'e Dong; Hanyi Yang. [Relation between Beta-2-glycoprotein I and hepatitis B virus surface antigen]. Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology (2002). PMID 11856498.