Acute colonic pseudo-obstruction (Ogilvie's syndrome) after renal transplantation.
PMID 10414701 · American journal of surgery · 1999 · DOI 10.1016/s0002-9610(99)00093-8
Authors: K J O'Malley; S M Flechner; A Kapoor; R A Rhodes; C S Modlin; D A Goldfarb; A C Novick
Abstract
Acute colonic pseudo-obstruction (Ogilvie's syndrome) in the immunosuppressed patient is associated with increased morbidity and mortality. Renal transplant recipients possess several comorbidities that increase the risk of acute pseudo-obstruction of the colon. The aims of this study were to present our experience with this syndrome and to evaluate the potentiating factors in these patients. A review of the literature for pseudo-obstruction following renal transplantation is presented. Seven patients who developed Ogilvie's syndrome were identified in a retrospective review of 550 kidney-only transplants. Pretransplant data, potential risk factors, presentation, management, and outcome details were retrieved. The medical literature was reviewed using Medline. Seventy-eight patients with Ogilvie's syndrome in the early posttransplant period have been reported. The associated morbidity and mortality was heightened in this immunocompromised population. Obese transplant recipients (body mass index >30 kg/m2) were at significantly increased risk for developing this syndrome. A broad armamentarium of treatment options is available, but the key to successful resolution lies in early recognition.
Colonic Pseudo-Obstruction; Comorbidity; Female; Humans; Immunosuppression Therapy; Kidney Transplantation; Male; Middle Aged; Obesity; Retrospective Studies; Risk Factors
Cite
K J O'Malley; S M Flechner; A Kapoor; R A Rhodes; C S Modlin; D A Goldfarb; A C Novick. Acute colonic pseudo-obstruction (Ogilvie's syndrome) after renal transplantation. American journal of surgery (1999). PMID 10414701. DOI 10.1016/s0002-9610(99)00093-8.